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Nancy Jean Cartwright (born October 25, 1957) is an American actress, voice actress and comedian, known for her long-running role as Bart Simpson on the animated television series The Simpsons. Cartwright also voices other characters for the show, including Nelson Muntz, Ralph Wiggum, Todd Flanders, Kearney and Database.
Cartwright was born in Dayton, Ohio. Cartwright moved to Hollywood in 1978 and trained alongside voice actor Daws Butler. Her first professional role was voicing Gloria in the animated series Richie Rich, which she followed with a starring role in the television movie Marian Rose White (1982) and her first feature film, Twilight Zone: The Movie (1983).
After continuing to search for acting work, in 1987, Cartwright auditioned for a role in a series of animated shorts about a dysfunctional family that was to appear on The Tracey Ullman Show. Cartwright intended to audition for the role of Lisa Simpson, the middle child; when she arrived at the audition, she found the role of Bart—Lisa's brother—to be more interesting. Matt Groening, the series' creator, allowed her to audition for Bart and offered her the role on the spot. She voiced Bart for three seasons on The Tracey Ullman Show, and in 1989, the shorts were spun off into a half-hour show called The Simpsons. For her subsequent work as Bart, Cartwright received a Primetime Emmy Award for Outstanding Voice-Over Performance in 1992 and an Annie Award for Best Voice Acting in the Field of Animation in 1995.
Besides The Simpsons, Cartwright has also voiced numerous other animated characters, including Daffney Gillfin in The Snorks, Rufus in Kim Possible, Mindy in Animaniacs, Pistol in Goof Troop, Margo Sherman in The Critic, Todd Daring in The Replacements, and Charles "Chuckie" Finster, Jr. in Rugrats and All Grown Up! (a role she assumed in 2002, following the retirement of Christine Cavanaugh). In 2000, she published her autobiography, My Life as a 10-Year-Old Boy, and four years later, adapted it into a one-woman play.

Source: Wikipedia